COPA Syndrome Foundation

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The COPA Syndrome Foundation is on a mission to discover how the COPA syndrome autoimmune disease damages the lungs, joints and other organs. Today very little is known about the disease. Our goal is to raise public awareness about this disorder and fund research and genetic testing to move forcefully toward improving treatment options and medications. We strive to offer hope, and ultimately a cure, for those suffering with the COPA syndrome, and to support their families who carry this genetic disease.

[/vc_column_text][vc_row_inner][vc_column_inner width=”1/1″][vc_empty_space][/vc_column_inner][/vc_row_inner][vc_row_inner id=”donate”][vc_column_inner width=”1/1″ desktop_alignment=”text-left”][pofo_section_heading pofo_heading_type=”heading-style2″ heading_preview_image=”heading-style2″ pofo_heading=”Would you like to Donate to COPA Syndrome Foundation?” pofo_title_font_size=”68″ pofo_title_color=”#00a651″][vc_column_text]If you would like to donate to COPA Syndrome Foundation please use the button below to donate through paypal, or you can donate by mailing a check to the address listed at the bottom of the page.[/vc_column_text][vc_empty_space height=”12px”][/vc_column_inner][/vc_row_inner][pofo_button pofo_button_style=”style1″ pofo_button_preview_image=”style1″ pofo_button_type=”large” pofo_button_text=”url:https%3A%2F%2Fwww.paypal.com%2Fcgi-bin%2Fwebscr%3Fcmd%3D_s-xclick%26hosted_button_id%3DR92FPJPBCMRZS%26source%3Durl|title:Donate!||” pofo_button_text_color=”#ffffff” pofo_button_icon_color=”#00a651″ pofo_button_hover_bg_color=”#5ce06c” css=”.vc_custom_1548187043960{background-color: #00a651 !important;}”][/vc_column][vc_column width=”1/12″ enable_clear_both=”1″ offset=”vc_col-lg-2 vc_col-md-2 vc_hidden-xs”][/vc_column][/vc_row][vc_row full_width=”stretch_row_content_no_spaces” equal_height=”yes” initial_loading_animation=”fadeIn” pofo_hidden_markup_1507182606_2_94=”” css=”.vc_custom_1519247152209{padding-top: 0px !important;padding-right: 0px !important;padding-bottom: 0px !important;padding-left: 0px !important;background-color: #f7f7f7 !important;}” id=”symptoms”][vc_column pofo_column_animation_style=”fadeInLeft” width=”1/2″ ipad_alignment=”sm-text-center” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507182606_2_28=”” alignment_setting=”1″ offset=”vc_col-md-6 vc_col-xs-12″][vc_row_inner pofo_enable_responsive_css=”1″ css=”.vc_custom_1509630892288{padding-top: 13% !important;padding-right: 13% !important;padding-bottom: 13% !important;padding-left: 13% !important;}” responsive_css=”padding_top_desktop:10%25|padding_right_desktop:10%25|padding_bottom_desktop:10%25|padding_left_desktop:10%25|padding_top_tablet:7%25|padding_right_tablet:7%25|padding_bottom_tablet:7%25|padding_left_tablet:7%25|padding_top_mobile:50px|padding_right_mobile:15px|padding_bottom_mobile:50px|padding_left_mobile:15px”][vc_column_inner width=”1/1″][pofo_section_heading pofo_heading_type=”heading-style2″ heading_preview_image=”heading-style2″ pofo_title_font_weight=”400″ pofo_title_element_tag=”h5″ pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507182606_2_11=”” pofo_hidden_markup_1498474489_2_38=”” pofo_hidden_markup_1498474255_2_67=”” pofo_hidden_markup_1498035492_2_5=”” pofo_hidden_markup_1498035415_2_72=”” pofo_hidden_markup_1498034903_2_39=”” pofo_heading=”Think you have COPA syndrome?” css=”.vc_custom_1525207364086{margin-bottom: 0px !important;}” responsive_css=”margin_bottom_mobile:5px”][pofo_section_heading pofo_heading_type=”heading-style2″ heading_preview_image=”heading-style2″ pofo_title_element_tag=”h5″ pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507182606_2_11=”” pofo_hidden_markup_1501490510_2_92=”” pofo_hidden_markup_1501483096_2_85=”” pofo_hidden_markup_1498474255_2_67=”” pofo_hidden_markup_1498035492_2_5=”” pofo_hidden_markup_1498035415_2_72=”” pofo_hidden_markup_1498034903_2_39=”” pofo_heading=”Here are some of the symptoms” css=”.vc_custom_1519189827608{margin-bottom: 8% !important;}” responsive_css=”margin_bottom_tablet:40px|margin_bottom_mobile:30px”][pofo_accordion pofo_accordion_style=”accordion-style2″ pofo_accordion=”%5B%7B%22pofo_accordion_title%22%3A%22Lung%20Disease%22%2C%22pofo_accordion_active%22%3A%221%22%2C%22pofo_content%22%3A%22COPA%20syndrome%20is%20typically%20diagnosed%20as%20Unknown%20Interstitial%20Lung%20Disease%20which%20can%20include%20hemorrhaging%20in%20the%20lungs.%22%7D%2C%7B%22pofo_accordion_title%22%3A%22Kidney%20Disease%22%2C%22pofo_content%22%3A%22Early%20symptoms%20of%20COPA%20syndrome%20include%20blood%20in%20urine%20and%20decreased%20urine%20output.%20Late%20symptoms%20include%20swelling%20due%20to%20fluid%20retention%20and%20shortness%20of%20breath.%20%22%7D%2C%7B%22pofo_accordion_title%22%3A%22Joint%20Problems%22%2C%22pofo_content%22%3A%22Along%20with%20lung%20disease%2C%20COPA%20syndrome%20can%20manifest%20as%20rheumatoid%20arthritis.%20Signs%20for%20COPA%20syndrome%20are%20pain%2C%20stiffness%20or%20swelling%20in%20joints%2C%20especially%20upon%20awakening.%22%7D%5D” pofo_hidden_markup_1498035785_2_14=”” pofo_title_color=”#46af56″ pofo_content_color=”#a25742″][/vc_column_inner][/vc_row_inner][/vc_column][vc_column width=”1/2″ css=”.vc_custom_1523659601174{background-color: #ededed !important;}”][vc_row_inner css=”.vc_custom_1523657049422{padding-top: 13% !important;padding-right: 13% !important;padding-bottom: 13% !important;padding-left: 13% !important;}”][vc_column_inner width=”1/1″][pofo_section_heading pofo_heading_type=”heading-style2″ heading_preview_image=”heading-style2″ pofo_title_font_weight=”400″ pofo_title_element_tag=”h5″ pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507182606_2_11=”” pofo_hidden_markup_1498474489_2_38=”” pofo_hidden_markup_1498474255_2_67=”” pofo_hidden_markup_1498035492_2_5=”” pofo_hidden_markup_1498035415_2_72=”” pofo_hidden_markup_1498034903_2_39=”” pofo_heading=”What is COPA Syndrome?” css=”.vc_custom_1525207258622{margin-bottom: 0px !important;}” responsive_css=”margin_bottom_mobile:5px” pofo_title_color=”#00a651″][vc_column_text]COPA syndrome is an inherited disorder caused by mutations in the coatomer subunit alpha gene, known as COPA.  The disorder usually appears early in childhood, and is usually characterized by a combination of severe lung disease and arthritis.  If someone suffers from a combination of these symptoms, they may want to consider being tested for COPA syndrome.

The childhood syndrome was only recently discovered when Houston pulmonologists shared research and connected the dots with a team of scientists at the University of California in San Francisco.  Their research was published in the April 20th, 2015 online edition of Nature Genetics.

Common complaints of onset in symptoms include difficulty breathing or joint pains due to arthritis.  Patients with COPA syndrome usually develop respiratory issues such as bleeding in the lungs or pulmonary hemorrhage or inflammation and scarring in the lungs know as interstitial lung disease (ILD). All patients with the COPA syndrome seem to eventually develop interstitial lung disease and arthritis over time.[/vc_column_text][/vc_column_inner][/vc_row_inner][/vc_column][vc_column][vc_row_inner][vc_column_inner width=”1/3″][/vc_column_inner][vc_column_inner width=”1/3″][pofo_section_heading pofo_heading_type=”heading-style2″ heading_preview_image=”heading-style2″ pofo_text_transform=”text-capitalize” pofo_heading=”What kinds of medical tests can a patient with COPA syndrome expect in the course of diagnosis and treatment?” pofo_title_color=”#00a651″][pofo_lists pofo_list_style=”list-style-1″ pofo_list_preview_image=”list-style-1″ pofo_list_values=”%5B%7B%22pofo_list_value%22%3A%22Blood%20tests%3A%20blood%20may%20be%20drawn%20to%20check%20for%20autoantibodies.%20Autoantibodies%20in%20patients%20include%20anti-neutrophil%20cytoplasmic%20antibodies%20(ANCA)%20such%20as%20anti-myeloperoxidase%20(MPO)%20or%20anti-proteinase%203%20(PR3)%20antibodies%2C%20and%20anti-nuclear%20antibodies%20(ANA).%20Also%20seen%20less%20commonly%20are%20cyclic%20citrullinated%20peptide%20(CCP)%20antibodies%20or%20rheumatoid%20factor%20(RF).%22%7D%2C%7B%22pofo_list_value%22%3A%22Chest%20imaging%20%E2%80%93%20either%20a%20CT%20scan%20of%20the%20chest%20or%20chest%20x-ray%20(CXR)%20can%20be%20used%20to%20look%20for%20lung%20disease%20and%20determine%20progression%20of%20lung%20disease.%22%7D%2C%7B%22pofo_list_value%22%3A%22Pulmonary%20function%20tests%20%E2%80%93%20breathing%20tests%20that%20assess%20how%20well%20the%20lungs%20are%20working.%22%7D%2C%7B%22pofo_list_value%22%3A%22Bronchoscopy%20exam%20%E2%80%93%20a%20procedure%20in%20which%20a%20thin%20tube%20with%20a%20camera%20is%20inserted%20into%20the%20lung%20to%20look%20at%20the%20lung%20tissue%20and%20to%20obtain%20lung%20tissue%20samples.%20The%20samples%20collected%20can%20include%20lung%20fluid%20and%20tissues%20to%20check%20for%20infections%2C%20the%20presence%20of%20bleeding%20and%20the%20types%20of%20immune%20cells.%22%7D%2C%7B%22pofo_list_value%22%3A%22Genetic%20testing%20%E2%80%93%20COPA%20syndrome%20is%20inherited%20and%20even%20early%20studies%20show%20that%20it%20runs%20in%20families.%20%20If%20you%20are%20diagnosed%20with%20COPA%20syndrome%20you%20should%20check%20with%20your%20doctor%20about%20genetic%20testing.%20You%20may%20be%20referred%20to%20a%20genetic%20counselor%2C%20or%20your%20doctor%20may%20want%20to%20discuss%20the%20case%20with%20one%20of%20the%20medical%20research%20labs%20studying%20the%20disorder.%22%7D%5D”][/vc_column_inner][vc_column_inner width=”1/3″][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row full_width=”stretch_row” initial_loading_animation=”fadeIn” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507183875_2_0=”” pofo_hidden_markup_1507183136_2_85=”” id=”treatment” css=”.vc_custom_1519247170575{padding-bottom: 8% !important;}” responsive_css=”padding_bottom_tablet:40px|padding_bottom_mobile:30px”][vc_column width=”1/6″ offset=”vc_col-lg-3 vc_col-md-3 vc_hidden-xs”][/vc_column][vc_column width=”2/3″ desktop_alignment=”text-center” alignment_setting=”1″ offset=”vc_col-lg-6 vc_col-md-6 vc_col-xs-12″][pofo_section_heading pofo_heading_type=”heading-style2″ heading_preview_image=”heading-style2″ pofo_text_transform=”text-uppercase” pofo_title_font_weight=”700″ pofo_title_element_tag=”h5″ pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507183875_2_12=”” pofo_hidden_markup_1501490960_2_11=”” pofo_hidden_markup_1501478875_2_4=”” pofo_hidden_markup_1498456477_2_21=”” pofo_hidden_markup_1498123231_2_60=”” pofo_hidden_markup_1498035944_2_57=”” pofo_hidden_markup_1498026732_2_74=”” pofo_heading=”How is copa syndrome treated?” css=”.vc_custom_1519190206876{margin-bottom: 20px !important;}” responsive_css=”margin_bottom_tablet:15px” pofo_title_color=”#00a651″][vc_column_text pofo_text_color=”#a25742″]

Patients are usually treated with medications that suppress the immune system known as immunosuppressive drugs, such as prednisone, rituximab or mycophenolate.  It is important to note that research on the syndrome is in the early stages and therefore scientist and doctors are still learning which treatments work best but one goal of this  foundation is to identify more patients so that more history and data can be compiled and shared. Talk with your doctor about available options.

[/vc_column_text][/vc_column][vc_column width=”1/6″ enable_clear_both=”1″ offset=”vc_col-lg-3 vc_col-md-3 vc_hidden-xs”][/vc_column][/vc_row][vc_row full_width=”stretch_row” initial_loading_animation=”fadeIn” id=”team”][vc_column width=”1/1″][vc_row_inner][vc_column_inner width=”1/6″ offset=”vc_col-lg-3 vc_col-md-3 vc_col-xs-12″][/vc_column_inner][vc_column_inner width=”2/3″ desktop_alignment=”text-left” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507199445_2_50=”” pofo_hidden_markup_1507197128_2_95=”” alignment_setting=”1″ offset=”vc_col-lg-6 vc_col-md-6 vc_col-xs-12″ css=”.vc_custom_1525207286124{margin-bottom: 15% !important;}” responsive_css=”margin_bottom_tablet:40px|margin_bottom_mobile:30px”][pofo_section_heading pofo_heading_type=”heading-style2″ heading_preview_image=”heading-style2″ pofo_text_transform=”text-uppercase” pofo_title_font_weight=”700″ pofo_title_element_tag=”h5″ pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507197128_2_47=”” pofo_hidden_markup_1501481437_2_60=”” pofo_hidden_markup_1498207018_2_10=”” pofo_hidden_markup_1498124755_2_26=”” pofo_hidden_markup_1498123442_2_28=”” pofo_hidden_markup_1498123231_2_60=”” pofo_hidden_markup_1498123002_2_14=”” pofo_hidden_markup_1498026732_2_74=”” pofo_heading=”Board of Directors” css=”.vc_custom_1526413951120{margin-bottom: 20px !important;}” responsive_css=”margin_bottom_tablet:15px” pofo_title_color=”#00a651″][vc_column_text pofo_text_color=”#a25742″]Current Board of Directors of the COPA Syndrome Foundation.[/vc_column_text][/vc_column_inner][vc_column_inner width=”1/6″ offset=”vc_col-lg-3 vc_col-md-3 vc_col-xs-12″][/vc_column_inner][/vc_row_inner][vc_row_inner][vc_column_inner pofo_column_animation_style=”slideInUp” width=”1/2″ desktop_alignment=”text-center” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507197128_2_95=”” alignment_setting=”1″ offset=”vc_col-md-3 vc_col-xs-12″ responsive_css=”margin_bottom_tablet:7%25|margin_bottom_mobile:40px”][pofo_team_member pofo_team_member_style=”team-2″ pofo_team_preview_image=”team-2″ pofo_enable_link=”1″ pofo_separator_height=”” pofo_hidden_markup_1498129117_2_100=”” pofo_team_member_image=”20944″ pofo_member_name=”Molly Plant” pofo_member_des=”President” pofo_member_name_color=”#80ddef” pofo_link_url=”https://www.copasyndrome.com/board-of-directors/molly-plant/” pofo_link_hover_color=”#81d742″][/pofo_team_member][/vc_column_inner][vc_column_inner pofo_column_animation_style=”slideInUp” width=”1/2″ desktop_alignment=”text-center” pofo_enable_responsive_css=”1″ height_setting=”1″ pofo_hidden_markup_1507197128_2_95=”” alignment_setting=”1″ offset=”vc_col-md-3 vc_col-xs-12″ pofo_column_animation_delay=”200″ responsive_css=”margin_bottom_tablet:7%25|margin_bottom_mobile:40px”][pofo_team_member pofo_team_member_style=”team-2″ pofo_team_preview_image=”team-2″ pofo_enable_link=”1″ pofo_separator_height=”” pofo_hidden_markup_1498130697_2_12=”” pofo_hidden_markup_1498129117_2_100=”” pofo_team_member_image=”20947″ pofo_member_name=”Renee Klimczak” pofo_member_des=”Secretary” pofo_member_name_color=”#80ddef” pofo_link_url=”https://www.copasyndrome.com/board-of-directors/renee-klimczak/” pofo_link_hover_color=”#81d742″][/pofo_team_member][/vc_column_inner][vc_column_inner ipad_clear_both=”sm-clear-both” pofo_column_animation_style=”slideInUp” width=”1/2″ desktop_alignment=”text-center” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507197128_2_95=”” alignment_setting=”1″ offset=”vc_col-md-3 vc_col-xs-12″ pofo_column_animation_delay=”400″ responsive_css=”margin_bottom_tablet:7%25|margin_bottom_mobile:40px”][pofo_team_member pofo_team_member_style=”team-2″ pofo_team_preview_image=”team-2″ pofo_separator_height=”” pofo_hidden_markup_1498130697_2_12=”” pofo_hidden_markup_1498129117_2_100=”” pofo_team_member_image=”21366″ pofo_member_name=”Tiffany Warwick” pofo_member_des=”Treasurer” 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pofo_member_name=”Beverly Hickman” pofo_member_des=”Board Member” pofo_member_name_color=”#80ddef”][/pofo_team_member][/vc_column_inner][vc_column_inner pofo_column_animation_style=”slideInUp” width=”1/2″ desktop_alignment=”text-center” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507197128_2_95=”” alignment_setting=”1″ offset=”vc_col-md-3 vc_col-xs-12″ responsive_css=”margin_bottom_tablet:7%25|margin_bottom_mobile:40px”][pofo_team_member pofo_team_member_style=”team-2″ pofo_team_preview_image=”team-2″ pofo_separator_height=”” pofo_hidden_markup_1498130697_2_12=”” pofo_hidden_markup_1498129117_2_100=”” pofo_team_member_image=”21276″ pofo_member_name=”Christopher Towe” pofo_member_des=”IT Specialist” pofo_member_name_color=”#80ddef”][/pofo_team_member][/vc_column_inner][/vc_row_inner][/vc_column][/vc_row][vc_row full_width=”stretch_row” initial_loading_animation=”fadeIn” css=”.vc_custom_1498136070941{background-color: #f7f7f7 !important;}” id=”blog”][vc_column 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border_size=”” pofo_token_class=”pofo_featurebox_1490093547-2-48″ pofo_feature_title=”Mailing Address” pofo_icon_list=”icon-map-pin”]

[/pofo_feature_box][/vc_column][vc_column pofo_column_animation_style=”fadeInUp” width=”1/4″ desktop_alignment=”text-center” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507197480_2_45=”” alignment_setting=”1″ offset=”vc_col-xs-12″ pofo_column_animation_delay=”200″ css=”.vc_custom_1517959715224{margin-bottom: 0px !important;}” responsive_css=”margin_bottom_tablet:50px|margin_bottom_mobile:30px”][pofo_feature_box pofo_feature_type=”featurebox19″ feature_box_preview_image=”featurebox19″ pofo_icon_size=”icon-medium” content_width_setting=”1″ pofo_feature_icon=”1″ pofo_hidden_markup_1498456134_2_31=”” pofo_hidden_markup_1498455347_2_10=”” pofo_hidden_markup_1498050356_2_81=”” pofo_hidden_markup_1498049878_2_73=”” pofo_hidden_markup_1498048542_2_11=”” pofo_hidden_markup_1496208624_2_43=”” border_color=”” border_size=”” pofo_token_class=”pofo_featurebox_1490093547-2-48″ pofo_feature_title=”Call Us” pofo_icon_list=”icon-chat” pofo_title_color=”#a25742″]Phone: 713-487-6364[/pofo_feature_box][/vc_column][vc_column pofo_column_animation_style=”fadeInUp” width=”1/4″ desktop_alignment=”text-center” pofo_enable_responsive_css=”1″ pofo_hidden_markup_1507197480_2_45=”” alignment_setting=”1″ offset=”vc_col-xs-12″ pofo_column_animation_delay=”400″ responsive_css=”margin_bottom_mobile:30px”][pofo_feature_box pofo_feature_type=”featurebox19″ feature_box_preview_image=”featurebox19″ pofo_icon_size=”icon-medium” content_width_setting=”1″ pofo_feature_icon=”1″ pofo_hidden_markup_1498456358_2_87=”” pofo_hidden_markup_1498455347_2_10=”” pofo_hidden_markup_1498050356_2_81=”” pofo_hidden_markup_1498049878_2_73=”” pofo_hidden_markup_1498048542_2_11=”” pofo_hidden_markup_1496208624_2_43=”” border_color=”” border_size=”” pofo_token_class=”pofo_featurebox_1490093547-2-48″ pofo_feature_title=”E-Mail Us!” pofo_icon_list=”icon-envelope”]info@copasyndrome.com[/pofo_feature_box][/vc_column][vc_column width=”1/4″ css=”.vc_custom_1523657673380{margin-left: 20% !important;}”][pofo_feature_box pofo_feature_type=”featurebox19″ feature_box_preview_image=”featurebox19″ pofo_enable_link=”1″ pofo_link_target=”_blank” pofo_link_on=”title” pofo_icon_list=”ti-facebook” pofo_feature_title=”Facebook” pofo_link_url=”https://www.facebook.com/COPASyndromeFoundation”]Click above to view our Facebook page![/pofo_feature_box][/vc_column][/vc_row]